AFAP1 Antibody (PACO15337)
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주문- SKU:
- PACO15337
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | AFAP1 Antibody (PACO15337) |
Antibody SKU: | PACO15337 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:25-1:100 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Fusion protein of human AFAP1 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using PACO15337(AFAP1 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200). |
![]() | Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: A172 cells, Primary antibody: PACO15337(AFAP1 Antibody) at dilution 1/134, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds. |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using PACO15337(AFAP1 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200). |
Background: | The protein encoded by this gene is a Src binding partner. It may represent a potential modulator of actin filament integrity in response to cellular signals, and may function as an adaptor protein by linking Src family members and/or other signaling proteins to actin filaments. Multiple transcript variants encoding different isoforms have been found for this gene. |
Synonyms: | Actin filament associated protein 1 |
UniProt Protein Function: | AFAP: Can cross-link actin filaments into both network and bundle structures. May modulate changes in actin filament integrity and induce lamellipodia formation. May function as an adapter molecule that links other proteins, such as SRC and PKC to the actin cytoskeleton. Seems to play a role in the development and progression of prostate adenocarcinoma by regulating cell-matrix adhesions and migration in the cancer cells. |
UniProt Protein Details: | Protein type:Adaptor/scaffold Chromosomal Location of Human Ortholog: 4p16 Cellular Component: focal adhesion; cytoplasm; actin cytoskeleton Molecular Function:actin binding Biological Process: regulation of signal transduction; regulation of cytoskeleton organization and biogenesis |
NCBI Summary: | The protein encoded by this gene is a Src binding partner. It may represent a potential modulator of actin filament integrity in response to cellular signals, and may function as an adaptor protein by linking Src family members and/or other signaling proteins to actin filaments. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008] |
UniProt Code: | Q8N556 |
NCBI GenInfo Identifier: | 166919564 |
NCBI Gene ID: | 60312 |
NCBI Accession: | Q8N556.2 |
UniProt Secondary Accession: | Q8N556,Q59EY5, Q9HBY1, A8K442, B4DMU2, E9PDT7, |
UniProt Related Accession: | Q8N556 |
Molecular Weight: | 730 |
NCBI Full Name: | Actin filament-associated protein 1 |
NCBI Synonym Full Names: | actin filament associated protein 1 |
NCBI Official Symbol: | AFAP1 |
NCBI Official Synonym Symbols: | AFAP; AFAP110; AFAP-110 |
NCBI Protein Information: | actin filament-associated protein 1; 110 kDa actin filament-associated protein; actin filament-associated protein, 110 kDa |
UniProt Protein Name: | Actin filament-associated protein 1 |
UniProt Synonym Protein Names: | 110 kDa actin filament-associated protein; AFAP-110 |
Protein Family: | Actin filament-associated protein |
UniProt Gene Name: | AFAP1 |
UniProt Entry Name: | AFAP1_HUMAN |
Antibodies | ELISA Kits |
Anti-AFAP1 Antibody (CAB3478) | Human AFAP1 (Actin Filament Associated Protein 1) ELISA Kit (HUES01521) |
AFAP1 Antibody (PACO07633) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |