AEBP2 Antibody (PACO43436)
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주문- SKU:
- PACO43436
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | AEBP2 Antibody (PACO43436) |
Antibody SKU: | PACO43436 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Zinc finger protein AEBP2 protein (248-517AA) |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Immunohistochemistry of paraffin-embedded human placenta tissue using PACO43436 at dilution of 1:100. |
Background: | DNA-binding transcriptional repressor. May interact with and stimulate the activity of the PRC2 complex, which methylates 'Lys-9' and 'Lys-27' residues of histone H3. |
Synonyms: | Zinc finger protein AEBP2 (Adipocyte enhancer-binding protein 2) (AE-binding protein 2), AEBP2 |
UniProt Protein Function: | AEBP2: DNA-binding transcriptional repressor. May interact with and stimulate the activity of the PRC2 complex, which methylates 'Lys-9' and 'Lys-27' residues of histone H3. Belongs to the AEBP2/jing C2H2-type zinc-finger family. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:C2H2-type zinc finger protein; Transcription, coactivator/corepressor; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 12p12.3 Cellular Component: nucleoplasm; ESC/E(Z) complex Molecular Function:metal ion binding; transcription corepressor activity Biological Process: transcription, DNA-dependent; negative regulation of gene expression, epigenetic; gene expression; negative regulation of transcription from RNA polymerase II promoter; chromatin modification; regulation of gene expression, epigenetic |
UniProt Code: | Q6ZN18 |
NCBI GenInfo Identifier: | 190358163 |
NCBI Gene ID: | 121536 |
NCBI Accession: | Q6ZN18.2 |
UniProt Secondary Accession: | Q6ZN18,Q59FS5, Q6ZN62, Q96BG3, |
UniProt Related Accession: | Q6ZN18 |
Molecular Weight: | 517 |
NCBI Full Name: | Zinc finger protein AEBP2 |
NCBI Synonym Full Names: | AE binding protein 2 |
NCBI Official Symbol: | AEBP2 |
NCBI Protein Information: | zinc finger protein AEBP2; AE-binding protein 2; adipocyte enhancer-binding protein 2; AE(adipocyte enhancer)-binding protein 2 |
UniProt Protein Name: | Zinc finger protein AEBP2 |
UniProt Synonym Protein Names: | Adipocyte enhancer-binding protein 2; AE-binding protein 2 |
Protein Family: | Zinc finger protein |
UniProt Gene Name: | AEBP2 |
UniProt Entry Name: | AEBP2_HUMAN |