ADRM1 Antibody (PACO47286)
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주문- SKU:
- PACO47286
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | ADRM1 Antibody (PACO47286) |
Antibody SKU: | PACO47286 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC, IF |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200, IF:1:50-1:200 |
Species Reactivity: | Human, Mouse |
Immunogen: | Recombinant Human Proteasomal ubiquitin receptor ADRM1 protein (2-407AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Western Blot. Positive WB detected in: Mouse stomach tissue. All lanes: ADRM1 antibody at 2.7µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 43 kDa. Observed band size: 43 kDa.. |
![]() | Immunofluorescent analysis of MCF-7 cells using PACO47286 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
![]() | Immunohistochemistry of paraffin-embedded human testis tissue using PACO47286 at dilution of 1:100. |
Background: | Functions as a proteasomal ubiquitin receptor. Recruits the deubiquitinating enzyme UCHL5 at the 26S proteasome and promotes its activity. |
Synonyms: | Proteasomal ubiquitin receptor ADRM1 (110 kDa cell membrane glycoprotein) (Gp110) (Adhesion-regulating molecule 1) (ARM-1) (Proteasome regulatory particle non-ATPase 13) (hRpn13) (Rpn13 homolog), ADRM1, GP110 |
UniProt Protein Function: | ADRM1: Functions as a proteasomal ubiquitin receptor. Recruits the deubiquitinating enzyme UCHL5 at the 26S proteasome and promotes its activity. Interacts with PSMD1, ubiquitin and UCHL5. Belongs to the ADRM1 family. |
UniProt Protein Details: | Protein type:Proteasome complex; Cell development/differentiation Chromosomal Location of Human Ortholog: 20q13.33 Cellular Component: proteasome complex; nucleoplasm; membrane; integral to plasma membrane; cytoplasm; plasma membrane Molecular Function:protein binding; protease binding Biological Process: RNA elongation from RNA polymerase II promoter; proteasome assembly |
NCBI Summary: | This gene encodes a member of the adhesion regulating molecule 1 protein family. The encoded protein is a component of the proteasome where it acts as a ubiquitin receptor and recruits the deubiquitinating enzyme, ubiquitin carboxyl-terminal hydrolase L5. Increased levels of the encoded protein are associated with increased cell adhesion, which is likely an indirect effect of this intracellular protein. Dysregulation of this gene has been implicated in carcinogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] |
UniProt Code: | Q16186 |
NCBI GenInfo Identifier: | 20141265 |
NCBI Gene ID: | 11047 |
NCBI Accession: | Q16186.2 |
UniProt Related Accession: | Q16186 |
Molecular Weight: | |
NCBI Full Name: | Proteasomal ubiquitin receptor ADRM1 |
NCBI Synonym Full Names: | adhesion regulating molecule 1 |
NCBI Official Symbol: | ADRM1 |
NCBI Official Synonym Symbols: | ARM1; ARM-1; GP110 |
NCBI Protein Information: | proteasomal ubiquitin receptor ADRM1 |
UniProt Protein Name: | Proteasomal ubiquitin receptor ADRM1 |
UniProt Synonym Protein Names: | 110 kDa cell membrane glycoprotein; Gp110; Adhesion-regulating molecule 1; ARM-1; Proteasome regulatory particle non-ATPase 13; hRpn13; Rpn13 homolog |
UniProt Gene Name: | ADRM1 |
UniProt Entry Name: | ADRM1_HUMAN |