ADH5 Antibody (PACO13474)
제품 코드를 사용하여 Assay Genie 메인 사이트를 통해 주문합니다.
주문- SKU:
- PACO13474
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Description
Antibody Name: | ADH5 Antibody (PACO13474) |
Antibody SKU: | PACO13474 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Human GSNOR,ADH5 |
Form: | Liquid |
Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | alcohol dehydrogenase 5 (class III), chi polypeptide;ADH5;ADH-3;ADHX;FDH;GSNOR ; |
UniProt Protein Function: | ADH5: Class-III ADH is remarkably ineffective in oxidizing ethanol, but it readily catalyzes the oxidation of long-chain primary alcohols and the oxidation of S-(hydroxymethyl) glutathione. Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. |
UniProt Protein Details: | Protein type:Energy Metabolism - methane; Oxidoreductase; Xenobiotic Metabolism - metabolism by cytochrome P450; EC 1.1.1.1; Lipid Metabolism - fatty acid; Mitochondrial; Carbohydrate Metabolism - glycolysis and gluconeogenesis; Xenobiotic Metabolism - drug metabolism - cytochrome P450; Amino Acid Metabolism - tyrosine; Cofactor and Vitamin Metabolism - retinol; EC 1.1.1.284 Chromosomal Location of Human Ortholog: 4q23 Cellular Component: mitochondrion; nucleus Molecular Function:protein homodimerization activity; electron carrier activity; zinc ion binding; formaldehyde dehydrogenase activity; alcohol dehydrogenase activity; S-(hydroxymethyl)glutathione dehydrogenase activity; fatty acid binding Biological Process: response to nitrosative stress; respiratory system process; ethanol catabolic process; formaldehyde catabolic process; peptidyl-cysteine S-nitrosylation; response to redox state; response to lipopolysaccharide; retinoid metabolic process; ethanol oxidation; positive regulation of blood pressure; aging |
NCBI Summary: | This gene encodes a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. The encoded protein forms a homodimer. It has virtually no activity for ethanol oxidation, but exhibits high activity for oxidation of long-chain primary alcohols and for oxidation of S-hydroxymethyl-glutathione, a spontaneous adduct between formaldehyde and glutathione. This enzyme is an important component of cellular metabolism for the elimination of formaldehyde, a potent irritant and sensitizing agent that causes lacrymation, rhinitis, pharyngitis, and contact dermatitis. The human genome contains several non-transcribed pseudogenes related to this gene. [provided by RefSeq, Oct 2008] |
UniProt Code: | P11766 |
NCBI GenInfo Identifier: | 113408 |
NCBI Gene ID: | 128 |
NCBI Accession: | P11766.4 |
UniProt Related Accession: | P11766 |
Molecular Weight: | |
NCBI Full Name: | Alcohol dehydrogenase class-3 |
NCBI Synonym Full Names: | alcohol dehydrogenase 5 (class III), chi polypeptide |
NCBI Official Symbol: | ADH5 |
NCBI Official Synonym Symbols: | FDH; ADHX; ADH-3; FALDH; GSNOR; GSH-FDH; HEL-S-60p |
NCBI Protein Information: | alcohol dehydrogenase class-3 |
UniProt Protein Name: | Alcohol dehydrogenase class-3 |
UniProt Synonym Protein Names: | Alcohol dehydrogenase 5; Alcohol dehydrogenase class chi chain; Alcohol dehydrogenase class-III; Glutathione-dependent formaldehyde dehydrogenase (EC:1.1.1.-); FALDH; FDH; GSH-FDH; S-(hydroxymethyl)glutathione dehydrogenase (EC:1.1.1.284) |
UniProt Gene Name: | ADH5 |
UniProt Entry Name: | ADHX_HUMAN |