ADH1B Antibody (PACO19072)
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주문- SKU:
- PACO19072
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | ADH1B Antibody (PACO19072) |
Antibody SKU: | PACO19072 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:100-1:300 |
Species Reactivity: | Human |
Immunogen: | Synthetic peptide of human ADH1B |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using PACO19072(ADH1B Antibody) at dilution 1/60, on the right is treated with synthetic peptide. (Original magnification: x200). |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO19072(ADH1B Antibody) at dilution 1/60, on the right is treated with synthetic peptide. (Original magnification: x200). |
Background: | The protein encoded by this gene is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. This encoded protein, consisting of several homo- and heterodimers of alpha, beta, and γ subunits, exhibits high activity for ethanol oxidation and plays a major role in ethanol catabolism. Three genes encoding alpha, β and γ subunits are tandemly organized in a genomic segment as a gene cluster. |
Synonyms: | alcohol dehydrogenase 1B (class I), β polypeptide |
UniProt Protein Function: | ADH1B: Dimer of identical or non-identical chains of three types; alpha, beta and gamma. Belongs to the zinc-containing alcohol dehydrogenase family. |
UniProt Protein Details: | Protein type:Lipid Metabolism - fatty acid; Carbohydrate Metabolism - glycolysis and gluconeogenesis; Xenobiotic Metabolism - metabolism by cytochrome P450; EC 1.1.1.1; Oxidoreductase; Amino Acid Metabolism - tyrosine; Cofactor and Vitamin Metabolism - retinol; Xenobiotic Metabolism - drug metabolism - cytochrome P450 Chromosomal Location of Human Ortholog: 4q23 Cellular Component: cytosol Molecular Function:zinc ion binding; alcohol dehydrogenase activity, zinc-dependent Biological Process: xenobiotic metabolic process; ethanol oxidation Disease: Alcohol Dependence |
NCBI Summary: | The protein encoded by this gene is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. This encoded protein, consisting of several homo- and heterodimers of alpha, beta, and gamma subunits, exhibits high activity for ethanol oxidation and plays a major role in ethanol catabolism. Three genes encoding alpha, beta and gamma subunits are tandemly organized in a genomic segment as a gene cluster. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013] |
UniProt Code: | P00325 |
NCBI GenInfo Identifier: | 113394 |
NCBI Gene ID: | 125 |
NCBI Accession: | P00325.2 |
UniProt Secondary Accession: | P00325,Q13711, Q4ZGI9, Q96KI7, A8MYN5, B4DRS9, B4DVC3 |
UniProt Related Accession: | P00325 |
Molecular Weight: | 375 |
NCBI Full Name: | Alcohol dehydrogenase 1B |
NCBI Synonym Full Names: | alcohol dehydrogenase 1B (class I), beta polypeptide |
NCBI Official Symbol: | ADH1B |
NCBI Official Synonym Symbols: | ADH2; HEL-S-117 |
NCBI Protein Information: | alcohol dehydrogenase 1B; ADH, beta subunit; aldehyde reductase; alcohol dehydrogenase subunit beta; epididymis secretory protein Li 117; alcohol dehydrogenase 2 (class I), beta polypeptide |
UniProt Protein Name: | Alcohol dehydrogenase 1B |
UniProt Synonym Protein Names: | Alcohol dehydrogenase subunit beta |
Protein Family: | Alcohol dehydrogenase |
UniProt Gene Name: | ADH1B |
UniProt Entry Name: | ADH1B_HUMAN |
Antibodies |
Anti-ADH1B Antibody (CAB1431) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |