ADGRG6 Antibody (PACO45405)
제품 코드를 사용하여 Assay Genie 메인 사이트를 통해 주문합니다.
주문- SKU:
- PACO45405
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | ADGRG6 Antibody (PACO45405) |
Antibody SKU: | PACO45405 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Adhesion G-protein coupled receptor G6 protein (40-300AA) |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Immunohistochemistry of paraffin-embedded human liver tissue using PACO45405 at dilution of 1:100. |
![]() | Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using PACO45405 at dilution of 1:100. |
Background: | G-protein coupled receptor which is activated by type IV collagen, a major constituent of the basement membrane. Essential for normal differentiation of promyelinating Schwann cells and for normal myelination of axons. |
Synonyms: | Adhesion G-protein coupled receptor G6 (Developmentally regulated G-protein-coupled receptor) (G-protein coupled receptor 126) (Vascular inducible G protein-coupled receptor) [Cleaved into: ADGRG6 N-terminal fragment (ADGRG6-NTF); ADGRG6 C-terminal fragment (ADGRG6-CTF)], ADGRG6, DREG GPR126 VIGR |
UniProt Protein Function: | G-protein coupled receptor which is activated by type IV collagen, a major constituent of the basement membrane. Couples to G(i)-proteins as well as G(s)-proteins (PubMed:24227709). Essential for normal differentiation of promyelinating Schwann cells and for normal myelination of axons (PubMed:24227709). Regulates neural, cardiac and ear development via G-protein- and/or N-terminus-dependent signaling. May act as a receptor for PRNP which may promote myelin homeostasis. |
NCBI Summary: | This gene, which is upregulated in human umbilical vein endothelial cells, encodes a G protein-coupled receptor. Variations in this gene can affect a person's stature. Multiple transcript variants encoding different proteins have been found for this gene. [provided by RefSeq, Mar 2009] |
UniProt Code: | Q86SQ4 |
NCBI GenInfo Identifier: | 215274152 |
NCBI Gene ID: | 57211 |
NCBI Accession: | Q86SQ4.3 |
UniProt Secondary Accession: | Q86SQ4,Q5TGN7, Q6DHZ4, Q6F3F5, Q6F3F6, Q6F3F7, Q6F3F8 Q6MZU7, Q8IXA4, Q8NC14, Q96JW0, |
UniProt Related Accession: | Q86SQ4 |
Molecular Weight: | 137kDa |
NCBI Full Name: | Adhesion G-protein coupled receptor G6 |
NCBI Synonym Full Names: | adhesion G protein-coupled receptor G6 |
NCBI Official Symbol: | ADGRG6 |
NCBI Official Synonym Symbols: | APG1; DREG; VIGR; LCCS9; PR126; GPR126; PS1TP2 |
NCBI Protein Information: | adhesion G-protein coupled receptor G6; G-protein coupled receptor 126 |
UniProt Protein Name: | Adhesion G-protein coupled receptor G6 |
UniProt Synonym Protein Names: | Developmentally regulated G-protein-coupled receptor |
Protein Family: | G-protein coupled receptor |
UniProt Gene Name: | ADGRG6 |