ADAP2 Antibody (PACO42218)
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주문- SKU:
- PACO42218
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | ADAP2 Antibody (PACO42218) |
Antibody SKU: | PACO42218 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA |
Recommended Dilutions: | |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Arf-GAP with dual PH domain-containing protein 2 protein (110-381AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Background: | GTPase-activating protein for the ADP ribosylation factor family (Potential). Binds phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and inositol 1,3,4,5-tetrakisphosphate (InsP4). Possesses a stoichiometry of two binding sites for InsP4 with identical affinity. |
Synonyms: | Arf-GAP with dual PH domain-containing protein 2 (Centaurin-alpha-2) (Cnt-a2), ADAP2, CENTA2 |
UniProt Protein Function: | CENTA2: GTPase-activating protein for the ADP ribosylation factor family (Potential). Binds phosphatidylinositol 3,4,5- trisphosphate (PtdInsP3) and inositol 1,3,4,5-tetrakisphosphate (InsP4). Possesses a stoichiometry of two binding sites for InsP4 with identical affinity. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Lipid-binding; Mitochondrial; GAPs; GAPs, ARF Chromosomal Location of Human Ortholog: 17q11.2 Cellular Component: mitochondrial envelope; cytoplasm; plasma membrane Molecular Function:protein binding, bridging; phosphatidylinositol-4,5-bisphosphate binding; protein binding; phosphatidylinositol-3,4,5-triphosphate binding; inositol 1,3,4,5 tetrakisphosphate binding; zinc ion binding; phosphatidylinositol-3,4-bisphosphate binding Biological Process: heart development; positive regulation of GTPase activity |
UniProt Code: | Q9NPF8 |
NCBI GenInfo Identifier: | 27923749 |
NCBI Gene ID: | 55803 |
NCBI Accession: | Q9NPF8.1 |
UniProt Secondary Accession: | Q9NPF8,Q8N4Q6, Q96SD5, |
UniProt Related Accession: | Q9NPF8 |
Molecular Weight: | 44,221 Da |
NCBI Full Name: | Arf-GAP with dual PH domain-containing protein 2 |
NCBI Synonym Full Names: | ArfGAP with dual PH domains 2 |
NCBI Official Symbol: | ADAP2 |
NCBI Official Synonym Symbols: | CENTA2; cent-b; HSA272195 |
NCBI Protein Information: | arf-GAP with dual PH domain-containing protein 2; centaurin beta; centaurin, alpha 2; centaurin-alpha 2 protein; centaurin-alpha-2; cnt-a2 |
UniProt Protein Name: | Arf-GAP with dual PH domain-containing protein 2 |
UniProt Synonym Protein Names: | Centaurin-alpha-2; Cnt-a2 |
Protein Family: | Arf-GAP with dual PH domain-containing protein |
UniProt Gene Name: | ADAP2 |
UniProt Entry Name: | ADAP2_HUMAN |