ADAMTS15 Antibody (PACO58328)
- SKU:
- PACO58328
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
| Antibody Name: | ADAMTS15 Antibody (PACO58328) |
| Antibody SKU: | PACO58328 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:200-1:500 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human A disintegrin and metalloproteinase with thrombospondin motifs 15 protein (801-913AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | IHC image of PACO58328 diluted at 1:400 and staining in paraffin-embedded human colon cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
| Synonyms: | A disintegrin and metalloproteinase with thrombospondin motifs 15 (ADAM-TS 15) (ADAM-TS15) (ADAMTS-15) (EC 3.4.24), ADAMTS15 |
| UniProt Protein Function: | ADAMTS15: Protein type: Motility/polarity/chemotaxis; Secreted, signal peptide; Secreted; EC 3.4.24.-; Protease; Extracellular matrixChromosomal Location of Human Ortholog: 11q25 |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature enzyme, which may play a role in versican processing during skeletal muscle development. This gene may function as a tumor suppressor in colorectal and breast cancers. [provided by RefSeq, May 2016] |
| UniProt Code: | Q8TE58 |
| NCBI GenInfo Identifier: | 48474504 |
| NCBI Gene ID: | 170689 |
| NCBI Accession: | Q8TE58.1 |
| UniProt Secondary Accession: | Q8TE58,Q32MI6 |
| UniProt Related Accession: | Q8TE58 |
| Molecular Weight: | 103,287 Da |
| NCBI Full Name: | A disintegrin and metalloproteinase with thrombospondin motifs 15 |
| NCBI Synonym Full Names: | ADAM metallopeptidase with thrombospondin type 1 motif 15 |
| NCBI Official Symbol: | ADAMTS15 |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | A disintegrin and metalloproteinase with thrombospondin motifs 15 |
| UniProt Protein Name: | A disintegrin and metalloproteinase with thrombospondin motifs 15 |
| UniProt Synonym Protein Names: | |
| Protein Family: | A disintegrin and metalloproteinase with thrombospondin motifs |
| UniProt Gene Name: | ADAMTS15 |
| UniProt Entry Name: | ATS15_HUMAN |
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