ACTR1A Antibody (PACO51302)
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주문- SKU:
- PACO51302
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | ACTR1A Antibody (PACO51302) |
Antibody SKU: | PACO51302 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Alpha-centractin protein (187-376AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Western Blot. Positive WB detected in: MCF-7 whole cell lysate. All lanes: ACTR1A antibody at 1µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 43 kDa. Observed band size: 43 kDa.. |
![]() | Immunohistochemistry of paraffin-embedded human pancreatic cancer using PACO51302 at dilution of 1:100. |
Background: | Component of a multi-subunit complex involved in microtubule based vesicle motility. It is associated with the centrosome. |
Synonyms: | Alpha-centractin (Centractin) (ARP1) (Actin-RPV) (Centrosome-associated actin homolog), ACTR1A, CTRN1 |
UniProt Protein Function: | ACTR1A: Component of a multi-subunit complex involved in microtubule based vesicle motility. It is associated with the centrosome. Belongs to the actin family. ARP1 subfamily. |
UniProt Protein Details: | Protein type:Cytoskeletal; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 10q24.32 Cellular Component: centrosome; cytoplasm; cytosol; microtubule associated complex; microtubule cytoskeleton Biological Process: antigen processing and presentation of exogenous peptide antigen via MHC class II; G2/M transition of mitotic cell cycle; vesicle-mediated transport |
NCBI Summary: | This gene encodes a 42.6 kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 8-13 copies per dynactin molecule, and is the most abundant molecule in the dynactin complex. It is an actin-related protein, and is approximately 60% identical at the amino acid level to conventional actin. [provided by RefSeq, Jul 2008] |
UniProt Code: | P61163 |
NCBI GenInfo Identifier: | 47117651 |
NCBI Gene ID: | 10121 |
NCBI Accession: | P61163.1 |
UniProt Secondary Accession: | P61163,P42024, B2R6B0, |
UniProt Related Accession: | P61163,AAB23391 |
Molecular Weight: | 42,614 Da |
NCBI Full Name: | Alpha-centractin |
NCBI Synonym Full Names: | ARP1 actin-related protein 1 homolog A, centractin alpha |
NCBI Official Symbol: | ACTR1A |
NCBI Official Synonym Symbols: | ARP1; Arp1A; CTRN1 |
NCBI Protein Information: | alpha-centractin |
UniProt Protein Name: | Alpha-centractin |
UniProt Synonym Protein Names: | ARP1; Actin-RPV; Centrosome-associated actin homolog |
Protein Family: | Alpha-centractin |
UniProt Gene Name: | ACTR1A |
UniProt Entry Name: | ACTZ_HUMAN |