UniProt Protein Function: | ACSBG1: Mediates activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Able to activate long-chain fatty acids. Also able to activate very long-chain fatty acids; however, the relevance of such activity is unclear in vivo. Can activate diverse saturated, monosaturated and polyunsaturated fatty acids. Belongs to the ATP-dependent AMP-binding enzyme family. Bubblegum subfamily. |
UniProt Protein Details: | Protein type:Ligase; EC 6.2.1.3 Chromosomal Location of Human Ortholog: 15q23-q24 Cellular Component: endoplasmic reticulum; cytoplasm; cytoplasmic membrane-bound vesicle Molecular Function:very-long-chain-fatty-acid-CoA ligase activity; ATP binding; long-chain-fatty-acid-CoA ligase activity Biological Process: myelination; ovarian follicle atresia; very-long-chain fatty acid metabolic process; response to glucocorticoid stimulus; long-chain fatty acid metabolic process |
NCBI Summary: | The protein encoded by this gene possesses long-chain acyl-CoA synthetase activity. It is thought to play a central role in brain very long-chain fatty acids metabolism and myelinogenesis. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q96GR2 |
NCBI GenInfo Identifier: | 27477105 |
NCBI Gene ID: | 23205 |
NCBI Accession: | NP_055977 |
UniProt Secondary Accession: | Q96GR2,O75126, Q76N27, Q9HC26, B2RB61, |
UniProt Related Accession: | Q96GR2 |
Molecular Weight: | |
NCBI Full Name: | long-chain-fatty-acid--CoA ligase ACSBG1 isoform 1 |
NCBI Synonym Full Names: | acyl-CoA synthetase bubblegum family member 1 |
NCBI Official Symbol: | ACSBG1 |
NCBI Official Synonym Symbols: | BG; BG1; BGM; LPD; GR-LACS |
NCBI Protein Information: | long-chain-fatty-acid--CoA ligase ACSBG1 |
UniProt Protein Name: | Long-chain-fatty-acid--CoA ligase ACSBG1 |
UniProt Synonym Protein Names: | Acyl-CoA synthetase bubblegum family member 1; hBG1; hsBG; hsBGM; Lipidosin |
Protein Family: | Long-chain-fatty-acid--CoA ligase |
UniProt Gene Name: | ACSBG1 |
UniProt Entry Name: | ACBG1_HUMAN |