ACOX3 Antibody (PACO15265)
제품 코드를 사용하여 Assay Genie 메인 사이트를 통해 주문합니다.
주문- SKU:
- PACO15265
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | ACOX3 Antibody (PACO15265) |
Antibody SKU: | PACO15265 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:5000, IHC:1:25-1:100 |
Species Reactivity: | Human |
Immunogen: | Fusion protein of human ACOX3 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using PACO15265(ACOX3 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: x200). | |
The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using PACO15265(ACOX3 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: x200). |
Background: | Acyl-Coenzyme A oxidase 3 also know as pristanoyl -CoA oxidase (ACOX3)is involved in the desaturation of 2-methyl branched fatty acid, in peroxisomes. Unlike the rat homolog, the human gene is expressed in very low amounts in liver such that its mRNA was undetectable by routine Northern-blot analysis or its product by immunoblotting or by enzyme activity measurements. However the human cDNA encoding a 700 amino acid, protein with a peroxisomal targeting C-terminal tripeptide S-K-L was isolated and is thought to be expressed under special conditions such as specific developmental stages or in a tissue specific manner in tissues that have not yet been examined. |
Synonyms: | acyl-CoA oxidase 3, pristanoyl |
UniProt Protein Function: | ACOX3: Oxidizes the CoA-esters of 2-methyl-branched fatty acids. Belongs to the acyl-CoA oxidase family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:EC 1.3.3.6; Lipid Metabolism - alpha-linolenic acid; Lipid Metabolism - fatty acid; Lipid Metabolism - unsaturated fatty acid biosynthesis; Oxidoreductase Chromosomal Location of Human Ortholog: 4p16.1 Cellular Component: membrane; peroxisomal matrix; peroxisome Molecular Function:acyl-CoA binding; acyl-CoA dehydrogenase activity; electron carrier activity; FAD binding; pristanoyl-CoA oxidase activity; receptor binding Biological Process: fatty acid beta-oxidation using acyl-CoA dehydrogenase; fatty acid beta-oxidation using acyl-CoA oxidase; lipid homeostasis |
NCBI Summary: | Acyl-Coenzyme A oxidase 3 also know as pristanoyl -CoA oxidase (ACOX3)is involved in the desaturation of 2-methyl branched fatty acids in peroxisomes. Unlike the rat homolog, the human gene is expressed in very low amounts in liver such that its mRNA was undetectable by routine Northern-blot analysis or its product by immunoblotting or by enzyme activity measurements. However the human cDNA encoding a 700 amino acid protein with a peroxisomal targeting C-terminal tripeptide S-K-L was isolated and is thought to be expressed under special conditions such as specific developmental stages or in a tissue specific manner in tissues that have not yet been examined. [provided by RefSeq, Jul 2008] |
UniProt Code: | O15254 |
NCBI GenInfo Identifier: | 156104864 |
NCBI Gene ID: | 8310 |
NCBI Accession: | NP_003492.2 |
UniProt Secondary Accession: | O15254,Q96AJ8, |
UniProt Related Accession: | O15254 |
Molecular Weight: | 69,575 Da |
NCBI Full Name: | peroxisomal acyl-coenzyme A oxidase 3 isoform a |
NCBI Synonym Full Names: | acyl-CoA oxidase 3, pristanoyl |
NCBI Official Symbol: | ACOX3 |
NCBI Protein Information: | peroxisomal acyl-coenzyme A oxidase 3 |
UniProt Protein Name: | Peroxisomal acyl-coenzyme A oxidase 3 |
UniProt Synonym Protein Names: | Branched-chain acyl-CoA oxidase; BRCACox; Pristanoyl-CoA oxidase |
Protein Family: | Peroxisomal acyl-coenzyme A oxidase |
UniProt Gene Name: | ACOX3 |
Antibodies |
Anti-ACOX3 Antibody (CAB17020) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |