ABCA2 Antibody (PACO51142)
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주문- SKU:
- PACO51142
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | ABCA2 Antibody (PACO51142) |
Antibody SKU: | PACO51142 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human ATP-binding cassette sub-family A member 2 protein (1223-1429AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Immunohistochemistry of paraffin-embedded human brain tissue using PACO51142 at dilution of 1:100. |
![]() | Immunohistochemistry of paraffin-embedded human melanoma using PACO51142 at dilution of 1:100. |
Background: | Probable transporter, its natural substrate has not been found yet. May have a role in macrophage lipid metabolism and neural development. |
Synonyms: | ATP-binding cassette sub-family A member 2 (ATP-binding cassette transporter 2) (ATP-binding cassette 2), ABCA2, ABC2 KIAA1062 |
UniProt Protein Function: | ABCA2: Probable transporter, its natural substrate has not been found yet. May have a role in macrophage lipid metabolism and neural development. Belongs to the ABC transporter superfamily. ABCA family. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Membrane protein, multi-pass; Membrane protein, integral; Transporter, ABC family; Transporter Chromosomal Location of Human Ortholog: 9q34 Cellular Component: cytoplasmic membrane-bound vesicle; endosome; integral to membrane; lysosome; membrane; microtubule organizing center Molecular Function:ATP binding; ATPase activity; ATPase activity, coupled to transmembrane movement of substances Biological Process: cholesterol efflux; cholesterol homeostasis; phospholipid efflux; regulation of intracellular cholesterol transport; regulation of transcription from RNA polymerase II promoter; response to drug; response to steroid hormone stimulus |
NCBI Summary: | The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This protein is highly expressed in brain tissue and may play a role in macrophage lipid metabolism and neural development. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9BZC7 |
NCBI GenInfo Identifier: | 206729923 |
NCBI Gene ID: | 20 |
NCBI Accession: | Q9BZC7.3 |
UniProt Secondary Accession: | Q9BZC7,Q5SPY5, Q5W9G5, Q76MW7, Q9HC28, A6NED5, |
UniProt Related Accession: | Q9BZC7 |
Molecular Weight: | 269,988 Da |
NCBI Full Name: | ATP-binding cassette sub-family A member 2 |
NCBI Synonym Full Names: | ATP binding cassette subfamily A member 2 |
NCBI Official Symbol: | ABCA2 |
NCBI Official Synonym Symbols: | ABC2 |
NCBI Protein Information: | ATP-binding cassette sub-family A member 2 |
UniProt Protein Name: | ATP-binding cassette sub-family A member 2 |
UniProt Synonym Protein Names: | ATP-binding cassette transporter 2; ATP-binding cassette 2 |
Protein Family: | ABC transporter A family |
UniProt Gene Name: | ABCA2 |
UniProt Entry Name: | ABCA2_HUMAN |