AARS2 Antibody (PACO13998)
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주문- SKU:
- PACO13998
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | AARS2 Antibody (PACO13998) |
Antibody SKU: | PACO13998 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:50-1:200 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Fusion protein of human AARS2 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO13998(AARS2 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200). |
![]() | Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: SP20 cells, Primary antibody: PACO13998(AARS2 Antibody) at dilution 1/600, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 15 seconds. |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human lymphoma tissue using PACO13998(AARS2 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200). |
Background: | The protein encoded by this gene belongs to the class-II aminoacyl-tRNA synthetase family. Aminoacyl-tRNA synthetases play critical roles in mRNA translation by charging tRNAs with their cognate amino acid, The encoded protein is a mitochondrial enzyme that specifically aminoacylates alanyl-tRNA. Mutations in this gene are a cause of combined oxidative phosphorylation deficiency 8. Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain |
Synonyms: | Alanyl-tRNA synthetase 2, mitochondrial |
NCBI Summary: | The protein encoded by this gene belongs to the class-II aminoacyl-tRNA synthetase family. Aminoacyl-tRNA synthetases play critical roles in mRNA translation by charging tRNAs with their cognate amino acids. The encoded protein is a mitochondrial enzyme that specifically aminoacylates alanyl-tRNA. Mutations in this gene are a cause of combined oxidative phosphorylation deficiency 8. [provided by RefSeq, Dec 2011] |
UniProt Code: | Q5JTZ9 |
NCBI GenInfo Identifier: | 38569417 |
NCBI Gene ID: | 57505 |
NCBI Accession: | NP_065796.1 |
UniProt Related Accession: | Q5JTZ9 |
Molecular Weight: | 108 kDa |
NCBI Full Name: | alanine--tRNA ligase, mitochondrial |
NCBI Synonym Full Names: | alanyl-tRNA synthetase 2, mitochondrial |
NCBI Official Symbol: | AARS2 |
NCBI Official Synonym Symbols: | AARSL; LKENP; COXPD8; MTALARS; MT-ALARS |
NCBI Protein Information: | alanine--tRNA ligase, mitochondrial |
UniProt Protein Name: | Alanine--tRNA ligase, mitochondrial |
UniProt Synonym Protein Names: | Alanyl-tRNA synthetase; AlaRS |
UniProt Gene Name: | AARS2 |
UniProt Entry Name: | SYAM_HUMAN |
Antibodies |
Anti-AARS2 Antibody (CAB7826) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |